产品货号：
Z37096
中文名称：
RHOA抗体
英文名称：
Anti-RHOA Antibody(Clone#2148CT124.4.9)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RHOA (Clone#2148CT124.4.9) |
| 指标别名 | ARH12;ARHA;h12;Rho cDNA clone 12;RHO12;RHOA;RHOH12;Transforming protein RhoA |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | RHOA |
| 克隆号 | 2148CT124.4.9 |
| 抗体来源 | Mouse |
| 免疫原 | This antibody is generated from a mouse immunized with a recombinant protein from human. |
| 计算分子量 | 22kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.Plays an essential role in cleavage furrow formation.Required for the apical junction formation of keratinocyte cell-cell adhesion.Stimulates PKN2 kinase activity.May be an activator of PLCE1.Activated by ARHGEF2,which promotes the exchange of GDP for GTP.Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.It controls the localization of APC and CLASP2 to the cell membrane,via the regulation of GSK3B activity.In turn,membrane-bound APC allows the localization of the MACF1 to the cell membrane,which is required for microtubule capture and stabilization.Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.Plays an essential role in cleavage furrow formation.Required for the apical junction formation of keratinocyte cell-cell adhesion.May be an activator of PLCE1.Activated by ARHGEF2,which promotes the exchange of GDP for GTP.Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.It controls the localization of APC and CLASP2 to the cell membrane,via the regulation of GSK3B activity.In turn,membrane-bound APC allows the localization of the MACF1 to the cell membrane,which is required for microtubule capture and stabilization (By similarity).Regulates KCNA2 potassium channel activity by reducing its location at the cell surface in response to CHRM1 activation;promotes KCNA2 endocytosis (PubMed:9635436,PubMed:19403695). |
| Uniprot ID | P61586 |
相关搜索：RHOA抗体，RHOA单抗，Anti-RHOA Antibody(Clone#2148CT124.4.9)